MyBioSource.com's HCN4 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: ELISA, and Western Blot. The HCN4 Antibody was generated using HCN4 as the antigen and it reacts with Human, Mouse, and Rat.
Description
Function: Hyperpolarization-activated ion channel with very slow activation and inactivation exhibiting weak selectivity for potassium over sodium ions. Contributes to the native pacemaker currents in heart (If) that regulate the rhythm of heart beat. May contribute to the native pacemaker currents in neurons (Ih). May mediate responses to sour stimuli.
Subunit Structure: Homotetramer. The potassium channel is composed of a homo-or heterotetrameric complex of pore-forming subunits.
Similarity: The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position. Belongs to the potassium channel HCN family